Mucus permeating thiolated self-emulsifying drug delivery systems
نویسندگان
چکیده
منابع مشابه
Mucus permeating thiolated self-emulsifying drug delivery systems.
CONTEXT Mucus represents a critical obstacle for self-emulsifying drug delivery systems (SEDDS) targeting the epithelial membrane site. OBJECTIVE The aim of the study was the development of a novel SEDDS to overcome the mucus barrier. MATERIALS AND METHODS Two novel conjugates N-dodecyl-4-mercaptobutanimidamide (thiobutylamidine-dodecylamine, TBA-D) and 2-mercapto-N-octylacetamide (thioglyc...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2016
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2015.11.004